Prof. dr. I. (Inge) Huitinga
Faculteit der Natuurwetenschappen, Wiskunde en Informatica
Swammerdam Institute for Life Sciences
Bezoekadres
- Science Park 904
Postadres
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Postbus 94232
1090 GE Amsterdam
Contactgegevens
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Publicaties
2024
Mekkes, N. J., Groot, M., Hoekstra, E., de Boer, A., Dagkesamanskaia, E., Bouwman, S., Wehrens, S. M. T., Herbert, M. K., Wever, D. D., Rozemuller, A., Eggen, B. J. L., Huitinga, I., & Holtman, I. R. (2024). Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine, 30(4), 1143-1153. https://doi.org/10.1038/s41591-024-02843-9 [details]- de Vries, L. E., Huitinga, I., Kessels, H. W., Swaab, D. F., & Verhaagen, J. (2024). The concept of resilience to Alzheimer's Disease: current definitions and cellular and molecular mechanisms. Molecular Neurodegeneration, 19(1), 33. https://doi.org/10.1186/s13024-024-00719-7
2023
- Hsiao, C. C., Engelenburg, H. J., Jongejan, A., Zhu, J., Zhang, B., Mingueneau, M., Moerland, P. D., Huitinga, I., Smolders, J., & Hamann, J. (2023). Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis. iScience, 26(1), Article 105785. https://doi.org/10.1016/j.isci.2022.105785 [details]
- International Multiple Sclerosis Genetics Consortium, & MultipleMS Consortium (2023). Locus for severity implicates CNS resilience in progression of multiple sclerosis. Nature, 619(7969), 323–331. https://doi.org/10.1038/s41586-023-06250-x
- Scheepstra, K. W. F., Mizee, M. R., van Scheppingen, J., Adelia, A., Wever, D. D., Mason, M. R. J., Dubbelaar, M. L., Hsiao, C. C., Eggen, B. J. L., Hamann, J., & Huitinga, I. (2023). Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia. Biological Psychiatry, 94(8), 619-629. https://doi.org/10.1016/j.biopsych.2023.04.020 [details]
- van den Bosch, A. M. R., Hümmert, S., Steyer, A., Ruhwedel, T., Hamann, J., Smolders, J., Nave, K. A., Stadelmann, C., Kole, M. H. P., Möbius, W., & Huitinga, I. (2023). Ultrastructural Axon–Myelin Unit Alterations in Multiple Sclerosis Correlate with Inflammation. Annals of Neurology, 93(4), 856-870. https://doi.org/10.1002/ana.26585 [details]
2021
- Zhang, L., Verwer, R. W. H., Zhao, J., Huitinga, I., Lucassen, P. J., & Swaab, D. F. (2021). Changes in glial gene expression in the prefrontal cortex in relation to major depressive disorder, suicide and psychotic features. Journal of Affective Disorders, 295, 893-903. https://doi.org/10.1016/j.jad.2021.08.098 [details]
2020
- Böttcher, C., van der Poel, M., Fernández-Zapata, C., Schlickeiser, S., Leman, J. K. H., Hsiao, C-C., Mizee, M. R., Adelia, Vincenten, M. C. J., Kunkel, D., Huitinga, I., Hamann, J., & Priller, J. (2020). Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis. Acta Neuropathologica Communications, 8, Article 136. https://doi.org/10.1186/s40478-020-01010-8 [details]
- Fransen, N. L., Hsiao, C-C., van der Poel, M., Engelenburg, H. J., Verdaasdonk, K., Vincenten, M. C. J., Remmerswaal, E. B. M., Kuhlmann, T., Mason, M. R. J., Hamann, J., Smolders, J., & Huitinga, I. (2020). Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions. Brain, 143(6), 1714-1730. https://doi.org/10.1093/brain/awaa117 [details]
- Korotkov, A., Puhakka, N., Das Gupta, S., Vuokila, N., Broekaart, D. W. M., Anink, J. J., Heiskanen, M., Karttunen, J., van Scheppingen, J., Huitinga, I., Mills, J. D., van Vliet, E. A., Pitkänen, A., & Aronica, E. (2020). Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation. Brain Pathology, 30(5), 897-912. Advance online publication. https://doi.org/10.1111/bpa.12865 [details]
- Zhang, L., Verwer, R. W. H., Lucassen, P. J., Huitinga, I., & Swaab, D. F. (2020). Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. Journal of Psychiatric Research, 121, 31-38. Advance online publication. https://doi.org/10.1016/j.jpsychires.2019.11.002 [details]
- Zhang, L., Verwer, R. W. H., Lucassen, P. J., Huitinga, I., & Swaab, D. F. (2020). Sex difference in glia gene expression in the dorsolateral prefrontal cortex in bipolar disorder: Relation to psychotic features. Journal of Psychiatric Research, 125, 66-74. Advance online publication. https://doi.org/10.1016/j.jpsychires.2020.03.003 [details]
- van der Poel, M., Hoepel, W., Hamann, J., Huitinga, I., & den Dunnen, J. (2020). IgG Immune Complexes Break Immune Tolerance of Human Microglia. The journal of immunology, 205(9), 2511-2518. https://doi.org/10.4049/jimmunol.2000130 [details]
2021
- Hsiao, C-C., Fransen, N. L., van den Bosch, A. M. R., Brandwijk, K. I. M., Huitinga, I., Hamann, J., & Smolders, J. (2021). White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue-resident memory T cells. European journal of immunology, 51(2), 483-486. Advance online publication. https://doi.org/10.1002/eji.202048665 [details]
2024
2021
2020
- Kalsbeek, M. J. T. (2020). Neuron-glia interactions in patients with type 2 diabetes. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
- van der Poel, M. (2020). Diversity of microglia: Their contribution to multiple sclerosis lesion formation. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications. Log in to Personal Page Publication Selection tool to manage the visibility of your publications on this list. -
Nevenwerkzaamheden
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Nederlands Herseninstituut KNAW
Afdelingsmanagement -
Nederlands Herseninstituut KNAW
Leider neuroimmunologische onderzoeksgroep
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Nederlands Herseninstituut KNAW
Mekkes, N. J., Groot, M., Hoekstra, E., de Boer, A., Dagkesamanskaia, E., Bouwman, S., Wehrens, S. M. T., Herbert, M. K., Wever, D. D., Rozemuller, A., Eggen, B. J. L., Huitinga, I., & Holtman, I. R. (2024). Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine, 30(4), 1143-1153.