My main interest lies in how neuromodulatory signals shape the neural computations underlying consciousness and decision-making in health and disease. I believe that the most exciting answers can be gained from research that actively integrates behavior, computation, and imaging of brain-wide networks with measurements and manipulations of neural circuits and individual neurons. To that end, my lab leverages a unique cross-species approach: ensemble (e.g. neuropixel) recordings, 2-photon imaging and optogenetics in mice, M/EEG and fMRI in humans, and pupillometry and computational modeling of behavior in both species.